农药的广泛使用给人类健康带来潜在的风险，儿童期许多疾患以及生长发育障碍，甚至成年的一些疾患，都怀疑与出生前的农药暴露有关联。然而，环境农药联合暴露与儿童精神健康的长期剂量效应反应关系仍不清楚。我们基于已经建立的前瞻性出生队列，探索儿童期农药长期暴露对儿童身体和精神健康的长期效应，为中国制定农药使用和减轻儿童期相关疾病风险的政策提供重要依据。项目在国家自然科学基金支持下，加强复旦大学公共卫生学院和瑞典卡罗琳斯卡医科大学环境医学研究所（IMM）的科研合作，建立学术联系与青年研究人员的培训和交流机制，促进相互间的了解与学术合作，推进在射阳县已经建立微型出生队列研究的深入，并探索研究生共同培养的可行途径和有效方法。项目的支持有利于双方合作创建一个跨学科研究团队，并推动IMM和复旦公共卫生学院更为广阔的合作平台建设。

Exposure to pesticides may induce potential health risks on humans due to their widespread use. Many childhood diseases such as growth and development dysfunction, and even some adult diseases have been suspected to be linked with prenatal pesticide exposure. However, the causality and dose-effect relationships between long-term environmental exposure to combined pesticides and mental health outcomes of children remain unclear. We aimed to explore the long-term effects of pesticides on physical and mental health during childhood based on a well-established prospective birth cohort study. Our findings will provide scientific evidence on making policies for reduced pesticide uses and childhood disease risks. With the support of NSFC-STINT, the scientific cooperation project between School of Public Health of Fudan University and Institute of Environmental Medicine (IMM) of Karolinska Institutet will focus on establishing academic links and promoting mutual understanding and scientific research communication among young researchers, and advancing the progress of mini birth cohort study performed at Sheyang County. It would be feasible and effective way for us to train graduate students together. It will benefit to create an interdisciplinary research team and provide for broader collaboration platform of IMM and School of Public Health, Fudan University.