一、未来探索：聚焦RNA结合蛋白、核孔蛋白、低密度脂蛋白受体相关蛋白、分选连接蛋白和Toll样受体蛋白家族等非通道蛋白或者细胞内物流系统分子，确立它们与心脏生物电稳态和心律失常发生的关系，并揭示其独特的机制特别是细胞生物学机制。二、战略目标：诞生新的理论或者新的假说——心脏生物电和心律失常的非通道调控理论假说；心脏节律的细胞内物流系统调控理论假说；心脏起搏细胞的起源和调控理论假说。三、完整技术体系的构建：完善和传承细胞内物流系统-心脏离子通道关系研究技术体系、心脏起搏细胞发育生物学研究技术体系和心脏生物电活动研究技术体系等。四、国际地位的创新群体的打造：形成由战略科学家引领的、由若干活跃在国际学术前沿的课题组长作为中流砥柱的、一大批中青年学者聚焦共同兴趣的、在国际上有重要一席地位的心律失常研究领域的创新研究群体。

1. Future exploration: Establish the role and function of non-channel proteins and molecules of intracellular logistic system in the homeostasis of heart bioelectricity and the development of arrhythmias, and uncover their unique mechanisms especially cell-biological mechanisms, with focuses on RNA-binding proteins, nucleoporins, low-density lipoprotein receptor-associated proteins, sorting nexins and toll-like receptors. 2. Strategic aim: Give birth to novel theories and/or novel hypotheses. For instance, the regulation theory (hypothesis) of heart bioelectricity and arrhythmias by non-channel proteins, the regulation theory (hypothesis) of heart rhythm by intracellular logistic system, and the theory (hypothesis) on the origin and regulation of cardiac pacemaker cells. 3. Complete technical system construction: Inherit and improve technical systems on studying the relation between intracellular trafficking system and cardiac ion channels, on studying the developmental biology of cardiac pacemaker cells, and on studying heart bioelectricalactivity. 4. Making an innovative research group of international standing: Form an innovative research community in heart rhythm and arrhythmia with important position in the world, guided by strategic scientists, enlivened by a number of principal investigators active in international academic frontier, and devoted by a large number of young and middle-aged scholars with common interests.