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自然疫源性疾病发现与溯源

自然疫源性疾病发现与溯源
  • 导航:首页 > 科学基金
  • 批准号:81621005
  • 批准年度: 2016年
  • 学科分类:传染病流行病学(H2609) |
  • 项目负责人:曹务春
  • 负责人职称:研究员
  • 依托单位:中国人民解放军军事医学科学院
  • 资助金额:1050万元
  • 项目类别:创新研究群体项目
  • 研究期限:2017年01月01日 至 2022年12月31日
  • 中文关键词: 自然疫源性疾病;发现;溯源
  • 英文关键词:Natural Focus Diseases;Epidemiology;Animal Hosts;Vectors;Exposed Population

项目摘要

中文摘要

研究团队紧紧围绕具有重要公共卫生意义和生物安全战略意义的自然疫源性疾病发现与溯源开展研究。最近5年,在世界上首次发现3种新蜱媒传染病,并阐明了病原及其自然疫源地特征;在欧洲以外最先报道3种蜱媒传染病,发现其传播媒介和宿主动物;揭示了埃博拉病毒演化及遗传多样性,阐明了埃博拉病毒病的传播动态和干预策略效果;最先发现H7N9流感病毒医院内传播,提示人与人之间传播的危险增大。在Nature、N Engl J Med、Lancet Infect Dis、Ann Intern Med、BMJ、PNAS、Clin Infect Dis、Emerg Infect Dis 等杂志联合发表发表SCI论文240篇,影响因子(IF)累计1108。全部论文在近5年内被SCI他引2518次。研究群体主要人员通力合作完成的科研成果“新发传染病综合防控技术体系的建立与应用”,2011年获国家科技进步一等奖。

英文摘要

The research team has been doing studies on discovery and tracing of natural focus diseases, which show significance in the aspects of public health and biosecurity. In the past 5 years, they have first discovered 3 emerging tickborne diseases in the world, and characterized the pathogens as well as natural foci. The other 3 emerging tickborne diseases have been first reported out of Europe. They have clarified the genomic diversity and evolution of Ebola virus in Sierra Leone, and characterized transmission dynamics and intervention effectiveness of Ebola virus disease. They first identified nosocomial transmission of avian influenza A (H7N9) virus in a hospital, and provided evidence of person to person transmission between unrelated individuals. Their papers have been published on the international peer-reviewed journals, including Nature、N Engl J Med、Lancet Infect Dis、Ann Intern Med、BMJ、PNAS、Clin Infect Dis、Emerg Infect Dis etc. Within the recent five years, a total of 240 SCI papers have been published with a total impact factor (IF) of 1108. The total citation was 2518 in the recent five years. Through close collaboration of the team members, their scientific achievement named “Establishment and Application of the Technical System for Comprehensive Prevention and Control of Emerging Infectious Diseases” was awarded the National First Class Prize for the Progress in Science and Technology in 2011.

评估说明

    国家自然科学基金项目“自然疫源性疾病发现与溯源”发布于爱科学iikx,并永久归类于相关科学基金导航中,仅供广大科研工作者查询、学习、选题参考。国科金是根据国家发展科学技术的方针、政策和规划,以及科学技术发展方向,面向全国资助基础研究和应用研究,发挥着促进我国基础研究源头创新的作用。国科金的真正价值在于它能否为科学进步和社会发展带来积极的影响。

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