过度自我觉知是指个体过度把自身当作注意对象时的心理状态，在抑郁症（major depressive disorder, MDD）发病、持续发作及短期复发中起着重要作用。中医松静功正是以自我觉知、自我调节为目的，我们前期研究发现，其能够引起默认网络（与自我觉知相关）成份改变，故提出中医松静功通过改变自我参照相关脑网络而实现纠正MDD过度自我觉知状态。本研究拟纳入符合标准的MDD患者60例，随机分配至松静功法组与肌肉放松组，干预6周。研究拟通过观察被试沉思反应、自动思维、自主神经活动、躯体症状感知及抑郁水平变化，分析中医松静功纠正过度自我觉知对抑郁状态改善的促进；通过静息态功能磁共振技术，探讨中医松静功对MDD自我参照相关脑网络改变；通过与肌肉放松训练相对比，探索中医松静功干预MDD特异性脑网络。本研究旨在为中医松静功优化MDD治疗和预防复发提供参考和依据，强化中医松静功应用与推广的理论基础。

Excessive self-awareness is a typical trait of depression. It plays critical role in occurrence, continuation, and relapse of major depressive disorder (MDD). Chinese medical relaxing and calming exercise focus on self-awareness and self-regulation. Our previous research demonstrated that Chinese medical relaxing and calming exercise can modify DMN networks in MDD. Thus, we hypothesize that Chinese medical relaxing and calming exercise can alter self-referential brain networks (default mode network, salience network, etc) to relieve excessive self-awareness. Our research will include 60 qualified MDD patients who will be assigned randomly into two groups: Chinese medical relaxing group and calming exercise group and relaxation group. The intervention lasts 6 weeks. Through observing changes of subjects’ rumination, automatic thoughts, automatic nerve activity, somatic symptom feeling and depressive level, to analyze the improvement in mental and physical by Chinese medical relaxing and calming exercise; Through resting functional magnetic resonance imaging technique to discuss self-referential brain networks’ alterations by Chinese medical relaxing and calming exercise; by comparing to relaxation training, to explore the specific networks of relaxing and calming exercise. The ultimate goal is to provide reference and proof for optimizing treatment, precaution relapse for MDD, which will strengthen theoretic basis for apply and propaganda Chinese medical relaxing and calming exercise.