本合作交流项目旨在通过与俄方科研人员合作，深化对冠心病患者心血管功能的定量评估方法研究。项目的主要目标是发展影像学数据与生物力学模型的融合技术来无创估测冠脉血流储备分数（FFR, Fractional Flow Reserve），同时实现对冠状动脉以及不同心肌层内血流灌注状态的量化评估，从而为冠脉循环的功能学诊断和临床决策提供有益的信息支持。项目执行过程中将充分利用中俄双方课题组的研究资源，进行优势互补，有机融合图像处理、生物力学建模、数值计算和临床检测方法，保障FFR估测系统的构建和验证工作按期完成。

The cooperation and exchange project is aimed to deepen the methodological study on quantitative assessment of cardiovascular function for patients with coronary arterial disease through collaborations with Russian researchers. The main target of the project is to realize noninvasive estimation of coronary fractional flow reserve (FFR) and quantitative evaluation of blood perfusion conditions in both coronary arteries and myocardium by developing techniques to fuse image data and biomechanical model. Outcomes of the study are expected to provide useful information supporting functional diagnosis and decision-making in the treatment of coronary arterial disease. The project will be implemented on the basis of a sufficient utilization of the research resources and complementary advantages available in both research groups to reach an effective integration of techniques in image treatment, biomechanical modeling, numerical computation and clinical diagnosis, thereby ensuring the on-schedule completion of the development and validation of the FFR estimation system.