申请人长期从事传染病流行病学研究，阐明了手足口病的季节性变化规律、疾病负担、重症和死亡结局的危险因素、疾病严重性等流行病学特征；揭示了A型和B型流感截然不同的季节性，确定了A(H1N1)pdm09的排毒规律，发现了B型流感较A型更为严重的死亡负担；确定了禽流感H7N9潜伏期，显著提高了估计的精确性，证明了其疾病谱存在“冰山现象”，疾病严重性低于H5N1，但比季节性流感高。.近5年，以第一或通讯作者（含并列）发表SCI论著32篇（含Lancet 3篇、BMJ 2篇、PLoS Med、Lancet ID和Nature Communications 各1篇），其中6篇配发了述评。近5年SCI他引1692次，单篇他引最高462次。其研究结果为建立对上述传染病基本流行特征的认识奠定了重要基础，为WHO和我国制定基于证据的防控措施提供了直接科学证据。2014年入选科技部“中青年科技创新领军人才”。

Hongjie Yu has conducted systematic, long-term studies on the epidemiology of infectious diseases. He has a series of important academic achievements with major contributions including: 1) elucidated basic epidemiologic characteristics of Hand, foot, and mouth disease, such as seasonal patterns, disease burden, clinical severity, and risk factors associated with severe and fatal outcomes, 2) discovered marked differences in seasonality of human infections with influenza A and B viruses, illustrated shedding dynamics of the newly emerged influenza A(H1N1)pdm09 virus, and demonstrated that influenza B-associated excess mortality was higher than influenza A-associated excess mortality, 3) provided an accurate estimate of the incubation period of human infection with the new avian influenza A(H7N9) virus, demonstrated the existence of a “clinical iceberg” phenomenon in avian influenza A(H7N9) virus infections, and quantified clinical severity of the avian influenza A(H7N9) virus infection which indicated the virus is not as severe as the avian influenza A(H5N1) virus, while more severe than the influenza A(H1N1)pdm09 and seasonal influenza viruses. ..He has published 32 research articles in the international peer-reviewed journals of the Science Citation Index (SCI) during the recent five years as first (joint first) author or corresponding (joint corresponding) author, including the Lancet (3), BMJ (2), PLoS Medicine (1), Lancet Infectious Diseases (1), and Nature Communications (1) with 6 editorial comments on his articles published in the same issues. His publications were cited 1692 times by others publications in the SCI with one most cited by 462 times. Findings of his research projects and studies have important scientific significance for establishing the knowledge and understandings of the basic epidemiological characteristics of the infectious diseases mentioned above, and have supplied essential scientific data to evidenced-based technical recommendations and public health decision making for preventing and controlling infectious diseases by the World Health Organization and Chinese governments. He was elected as one of leading young scientists for research and innovation by Chinese Ministry of Science and Technology in 2014.