该项目是基于SHP2酶结构设计、合成及活性筛选新型抗白血病药物并进行其抗癌机理研究。通过项目合作交流，增进中瑞双方在科研及教学方面的相互了解，将双方申请人的实验平台的功能及技术有机结合，实现创新药物研究从设计、合成到活性筛选的完美结合，达到优势互补。为今后建立广泛的科研及教学合作奠定基础。

The aim of this project is to discover novel anticancer drugs based on the design, synthesis and bioactivity screening of the protein tyrosine phosphatase SHP2 and to study the anticancer mechanism. Applying the SSSTC is to enhance mutual understanding in terms of scientific research and teaching to let Li’s bioactivity lab and Wang’s CADD and synthesis lab complement each other, finally to achieve the goal to study the novel drug from design，synthesis and biological activities. It will lay the foundation for the further scientific research and teaching partnership.