蓝果树属植物物种间断分布于东亚和北美地区，既有广布物种也有极小种群物种，是集众多进化科学问题为一体的优秀模式系统。本项目拟完成该属物种的种群基因组重测序，并分别利用种群基因组学与系统发育基因组学方法构建物种关系，阐明该属的生物地理间断分布过程以及物种对各区域气候变化响应等重要的进化式样。此外，将针对传统的系统发育学分析方法，建立从单个个体多位点溯祖模型到多个个体（种群）多位点的新模型和分析方法。本项目的完成不仅为使用基因组数据研究进化问题提供一个新的方向，也将为利用种群基因组数据研究物种关系建立新的分析方法。

Nyssa is one of the plant genera with a disjunct distribution in eastern Asia and North America. It contains not only widely distributed species but also plant species with extremely small populations. Therefore, it is an excellent model system for answering a variety of evolutionary questions. Here, we propose population-based re-sequencing of Nyssa. We will infer the species relationships using both population genomic and phylogenomic methods. For Nyssa, we aim to elucidate (1) historical causes of disjunct biogeographic distributions and (2) evolutionary patterns of how species respond to regional climate change. In addition, we will establish a new multilocus coalescent model using multiple individuals per species, which is fundamentally different from traditional phylogenetic methods using only one individual per species. The completion of this project not only provides a new direction for understanding evolutionary processes with genomic data, but also establishes a new method to infer species relationships using population genomic data.