中文摘要
细胞骨架是当前植物学研究领域的热点之一。申请人一直从事植物微丝骨架相关研究,发现和报道了多个新的、植物特有的微丝结合蛋白家族,揭示了这些微丝结合蛋白在花粉管极性生长和植物响应非生物胁迫过程中的生理生化功能;阐明了它们调控植物高级微丝结构形成和动态的分子机制;揭示了被子植物ADF家族的演化模式和功能分化机制。与此相关的主要研究成果发表在The Plant Cell、Molecular Plant、Journal of Biological Chemistry等国际主流期刊,并受到国内外同行的广泛认可和引用。申请人入选了教育部“新世纪优秀人才计划”(2013)和“甘肃省杰出青年基金”(2013)。. 申请人拟系统研究两个植物特有ABPs在植物干旱胁迫中的生理功能、信号转导过程和调控微丝机制机制,进一步深入探索微丝骨架参与植物响应和抵御逆境胁迫的的分子机理,具有重要的科学价值。
英文摘要
In plant cells, the cytoskeleton play vital roles in numerous cellular processes; thus, the related research is a hot topic in the research field of Botany. The applicant has been engaged in the research on plant actin cytoskeleton for many years, and successively reported several new plant-specific actin binding protein families for the following research works: 1) demonstrated that these ABPs participate in some significant physiological activities, such as pollen tube growth and multiple abiotic stress responses; 2) clarified their molecular mechanisms of regulating the formation of higher-ordered microfilament structure, such as actin bundle; 3) revealed the evolutionary patterns and neofunctionalization mechanism in the evolution of ADFs. The major results have been published in the international journals such as Plant Cell, Molecular Plant, Journal of Biological Chemistry and so on. And the applicant was supported by Program for New Century Excellent Talents of Ministry of Education (2013) as well as Funding for Gansu Province Distinguished Young Scholars (2013), respectively.. Our project based on the previous research work by applicant intends to further expose the molecular mechanism of actin cytoskeleton involved in plant response and/or resistance to environmental stresses. The expected results might also provide new ideas for correlative research on the mechanisms of plant stresses-tolerance, which possess important significance in both theory and practice.
