西藏桃儿七（Sinopodophyllum emodi (Wall.) Ying）隶属于小蘗科（Berberidaceae）鬼臼亚科（Podophylloideae），为多年生草本植物。长期生长于高原环境使其积累较多的次生代谢产物。由于受到极端气候、人为干扰等不利因素的影响，导致目前此资源濒临灭绝，相关研究仍处于初级阶段。本项目拟借助植物学、分子生物学及生物化学等手段对西藏桃儿七进行系统研究，主要内容包括：（1）野生居群生境调查及植物学特征研究；（2）物种及居群水平上的遗传多样性分析；（3）野生居群鬼臼毒素含量测定及其与遗传和环境因子间的相关性；（4）核心种质的初步构建。本项目研究结果将为该宝贵种质资源的保护和可持续开发利用奠定基础。

Tibetan Sinopodophyllum emodi (Wall.) Ying is a perennial herb within the family Berberidaceae. The long-term growth under the plateau conditions has resulted in its high accumulation of secondary metabolites. Largely due to the extreme climate and anthropogenic disturbance, this germplasm resource is on the verge of extinction. This project investigates Tibetan S. emodi through an integrated application of botanical, molecular biology and biochemical approaches. The major objectives are to: (1) characterize its natural habitats and botanical traits; (2) estimate the level and partitioning of its genetic variability at both population and species levels; (3) determine podophyllotoxin contents of its natural population, and evaluate the relative importance of genetic and environmental factors in the accumulation of podophyllotoxin; and (4) establish the core germplsm. The findings of this project would provide bases for the formulation of effective conservation and the sustainable utilization of this valuable plant germplasm.