果蝇作为模式生物，其分子系统发育及进化生物学得到了广泛深入的研究，但是，大多集中在果蝇亚科果蝇属及其近缘属上。冠果蝇亚科是较早从果蝇的进化主干上分化出来的类群，且广泛地分布在亚洲东部地区。我们研究发现，伏果蝇属Phortica和冠果蝇属 Stegana是本亚科的较早分化出来的类群，它们生殖器构造复杂，变化多样，种类多，种团多，亚属多。对这二个属及其近缘属的深入研究，对认识果蝇科的早期分化与适应辐射是及其重要的。近三年来，我们对转录组进行了详细地研究，得到了6属12种冠果蝇的序列，暂时发现五个核内基因序列对分析系统发育关系有重要作用，现已得到这些核基因的引物，奠定了本研究实验基础。中国及亚洲东部地区分布有本亚科15属（含四大属及主要类群）近600种（全世界有28属近900种），是多样性最为丰富的地区。我们采集到了13属约540种，奠定了本研究材料基础，其研究结果具有较好的代表性和科学价值。

Drosophila as one model organism has been extensively studied on molecular phylogeny and evolutionary biology, however, the most studies are constrained in the subfamily Drosophilinae and closely related species other than the subfamily Steganinae which is proposed to branch early in the whole family and widely distributes in eastern Asia. Within the subfamily Steganinae, the genera Phortica and Stegana originated early showing complex terminalia in a variety of formations and abundant species, species complex and subgenera were recognized within these two genera. Comprehensive studies on the Phortica and Stegana should show lights into the early speciation and adaptive radiation within the family Drosophilidae. Through the transcriptomics study on the 12 species affiliated with 6 genera of subfamily Steganinae in the past three years, initial results indicate that five nuclear genes are informative for the phylogenetic analysis. The primers targeting on these five nuclear genes have been designed by us. This laid the solid foundation for the further study on phylogeny of the subfamily Steganinae. In addition, fifteen genera including four largest genera and main clades represented by approximate 600 species have been recorded in China and other eastern Asian areas, in contrast to almost 900 species belonging to 28 genera observed in the whole world suggesting that eastern Asia is the region with the most abundant diversity. Thus far, 540 species of 13 genera have been sampled by us, providing one great opportunity for the future phylogenetic study on the subfamily Steganinae. This study should contribute a lot to the phylogenetics and evolutionary biology in the whole family exhibiting invaluable scientific merits.