中国大学生艾滋病感染率呈快速增长，目前仍缺乏对学生感染者社交网络特征的刻画，针对高校重点人群的防控模式尚待完善。我们前期研究表明，大学生对艾滋病疫情严重性、不安全性行为等认知与关注不足，男生自报初次性行为性伴为同性的比例高达10%。本研究拟以青年学生艾滋病疫情严重的四个城市为研究现场，以大学生感染者为种子研究人群，追溯其HIV传播途径，了解其不同社交子群的网络特征及其大众意见领袖（POL）的筛选路径，分析子群HIV感染的共性和特异性影响因素；在创新扩散和生活技能教育理论基础上整合形成“生活技能获得－同伴地位提高－干预效果增强”的轴线干预模型，动员培训POL，增强其对同伴干预技能，提高同伴预防艾滋病相关的心理社会能力，减少危险行为，主动寻求HIV检测与咨询，预防HIV二代传播。研究的实施既为构建我国大学生HIV感染不同社交网络模型进行一次积极的理论探索，也为高校学生艾滋病防控提供有效模式。

HIV prevalence rate among Chinese college students has been ever increasing rapidly. Very few studies are aimed at the characteristics of social network (SN) of HIV positive college students. We need address that via an effective model to contain HIV transmission among the key population on campus. Our previous studies showed that college students’ awareness of and attention to the severity of HIV/AIDS were insufficient. The self report proportion of male students’ sexual debut with a man was very high up to 10%. This study will be conducted among college students in four HIV severely impacted cities. We will use HIV positive college students as seeds to trace the transmission route to understand the characteristics of different subnetwork as well determine the selection of public opinion leaders (POL). We will explore the predictors of HIV infection among the students by analysis of the generality and specificity of different subnetwork. In addition, we will develop an intervention model with the logic path to achieve a better intervention via increase peer status of the POL based on life-skills training per the theory of Diffusion of Innovation and Life Skills Education. We will identify and train the POL to increase their intervention skills and help them influence their peers with better psycho-social competence and reducing risk behaviors. By doing this, we can motivate more college students to seek HIV testing and counseling voluntarily and contain HIV secondary transmission. We attempts to have a theory exploration on HIV prevention and intervention among college students based on social network and subnetwork analysis to inform policy making in HIV response on college campus.