中文摘要
放射诊疗是医学科学发展很快的领域,尤以X-CT不断更新而成就了医学诊治水平的突破。但新近多排螺旋CT适应发展需要而采用宽探测器,致使已有的监测评价方法遭遇难解,故亟需立项针对性攻克宽探测器螺旋CT所致辐射剂量的科学实用评价方法,进而深入研究其广泛应用中既获取最佳影像质量又合理减少所致患者剂量,以实现趋利避害,并促进宽探测器CT在医学诊断中充分发挥作用。项目组在已有工作基础上,拟通过现场监测和人体模型模拟实验研究,运用循证医学和放射防护最优化理论与方法,综合测试分析宽探测器CT剂量分布曲线等,确立其剂量表征量及监测方法,并寻求其与所致患者器官剂量及有效剂量的转换关系。研究结果还可在国内、外率先建立宽探测器螺旋CT医疗照射指导(参考)水平。从放射学和放射医学相关新进展中提炼出的此前沿课题,体现了多学科交叉的突出特色和迫切的社会需要,并必将有力推动放射医学与防护学科和放射诊疗事业的更好发展。
英文摘要
Radiology is one of the extremely rapid development field of medicine,especially in X-CT constantly achievements of medical diagnosis and treatment. But the use of increasingly wide X ray scanning beams in spiral CT are presenting problems in dosimetry that currently cannot be adequately addressed by existing methods for wide beam spiral CT, so it is important to study the evaluation method for radiation dose of wide beam spiral CT, and its application to obtain the best image quality and reduce patient doses. This study will help to reduce the radiation risk of wide beam spiral CT, and promote to play its role better in medical diagnosis. Based on the previous research work, this study will field survey the procedures of clinical application of wide beam spiral CT combining human body phantom experiment, test and evaluate the dose porfile of wide beam spiral CT,measure the organ dose and calculate the effective dose, establish the dose indicator for wide beam spiral CT and its conversion factor for organ dose and effective dose by using evidence-based medicine and radiation protection optimization theory and method.The results can also take the lead in establishing guidance(reference) level for medical exposure of wide beam spiral CT in the world. This leading issue reflects the multidisciplinary specialty, meets the needs of the community, and will significantly promote the development of radiological medicine and protection.
结题摘要
放射诊疗是医学科学发展很快的领域,尤以X-CT不断更新而成就了医学诊治水平的突破。但新近多排螺旋CT适应发展需要而采用宽探测器,致使已有的监测评价方法遭遇难解,故亟需立项针对性攻克宽探测器螺旋CT所致辐射剂量的科学实用评价方法,进而深入研究其广泛应用中既获取最佳影像质量又合理减少所致患者剂量,以实现趋利避害,并促进宽探测器CT在医学诊断中充分发挥作用。项目组在已有工作基础上,通过现场监测和人体模型模拟实验研究,运用循证医学和放射防护最优化理论与方法,综合测试分析宽探测器CT剂量分布曲线等,确立了宽探测器螺旋CT所致辐射剂量新表征量及监测方法,并初步确立宽探测器螺旋CT所致辐射剂量新表征量与现有多排螺旋CT辐射剂量标准量的转换关系,率先建立了宽探测器螺旋CT医疗照射指导(参考)水平。从放射学和放射医学相关新进展中提炼出的此前沿课题,体现了多学科交叉的突出特色和迫切的社会需要,并必将有力推动放射医学与防护学科和放射诊疗事业的更好发展。
